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    Promethazine is used with other medications to treat anaphylaxis (sudden, severe allergic reactions) and the symptoms of the common cold such as sneezing, cough, and runny nose. Promethazine helps control symptoms, but will not treat the cause of the symptoms or speed recovery. Instead, the best way to dispose of your medication is through a medicine take-back program.

    Talk to your doctor if you think you might be pregnant while you are taking promethazine. Promethazine is also used to prevent and control nausea and vomiting that may occur after surgery, and with other medications to help relieve pain after surgery. If you experience any of the following symptoms, call your doctor immediately swelling of the face, eyes, lips, tongue, throat, arms, hands, feet, ankles, or lower legs if you experience a serious side effect, you or your doctor may send a report to the food and drug administrations (fda) medwatch adverse event reporting program online ( promethazine may cause other side effects.

    Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Also tell your doctor and pharmacist if you have ever had an unusual or unexpected reaction when you took promethazine, another phenothiazine, or any other medication.

    Promethazine may also be taken at bedtime the night before surgery to relieve anxiety and produce quiet sleep. Keep this medication in the carton or container it came in, tightly closed, and out of reach of children. Ask your doctor or pharmacist if you do not know if a medication you are allergic to is a phenothiazine.

    When promethazine is used to treat motion sickness, it is taken 30 to 60 minutes before travel and again after 8 to 12 hours if needed. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. When promethazine is used to relieve cold symptoms, it is usually taken every 4 to 6 hours as needed.

    This medication may be prescribed for other uses ask your doctor or pharmacist for more information. Promethazine comes as a tablet and syrup (liquid) to take by mouth and as a suppository to use rectally. If you are taking promethazine liquid, do not use a household spoon to measure your dose. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Be sure to mention any of the following antidepressants (mood elevators) such as amitriptyline (elavil), amoxapine (asendin), clomipramine (anafranil), desipramine (norpramin), doxepin (adapin, sinequan), imipramine (tofranil), nortriptyline (aventyl, pamelor), protriptyline (vivactil), and trimipramine (surmontil) antihistamines azathioprine (imuran)barbiturates such as phenobarbital (luminal) cancer chemotherapy epinephrine (epipen) ipratropium (atrovent)medications for anxiety, irritable bowel disease, mental illness, motion sickness, parkinsons disease, seizures, ulcers, or urinary problems monoamine oxidase (mao) inhibitors such as isocarboxazid (marplan), phenelzine (nardil), tranylcypromine (parnate), and selegiline (eldepryl, emsam, zelapar) narcotics and other pain medication sedatives sleeping pillsand tranquilizers.


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    If you are giving promethazine to a child, watch the child to be sure he or she does not get hurt while riding a bike or participating in other activities that could be dangerous. When promethazine is used to relieve cold symptoms, it is usually taken every 4 to 6 hours as needed. Store promethazine tablets and liquid at room temperature and away from excess heat and moisture (not in the bathroom). Promethazine is used to relieve the symptoms of allergic reactions such as allergic rhinitis (runny nose and watery eyes caused by allergy to pollen, mold or dust), allergic conjunctivitis (red, watery eyes caused by allergies), allergic skin reactions, and allergic reactions to blood or plasma products. Use the measuring spoon or cup that came with the medication or use a spoon made especially for measuring medication.

    . Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking promethazine. When promethazine is used to treat motion sickness, it is taken 30 to 60 minutes before travel and again after 8 to 12 hours if needed. Tell your doctor or pharmacist about all the medications your child is taking, especially barbiturates such as phenobarbital (luminal), medications for anxiety, narcotic medications for pain, sedatives, sleeping pills, and tranquilizers. On longer trips, promethazine is usually taken in the morning and before the evening meal on each day of travel.

    Do not drive a car or operate machinery until you know how this medication affects you. Do not try to swallow the suppositories or insert in any other part of your body. Ask your doctor or pharmacist if you do not know if a medication you are allergic to is a phenothiazine. Promethazine should not routinely be used to treat vomiting in children it should only be used in specific cases when a doctor decides that it is needed. Instead, the best way to dispose of your medication is through a medicine take-back program. When promethazine is used to treat or prevent nausea and vomiting it is usually taken every 4 to 6 hours as needed. Be sure to mention any of the following antidepressants (mood elevators) such as amitriptyline (elavil), amoxapine (asendin), clomipramine (anafranil), desipramine (norpramin), doxepin (adapin, sinequan), imipramine (tofranil), nortriptyline (aventyl, pamelor), protriptyline (vivactil), and trimipramine (surmontil) antihistamines azathioprine (imuran)barbiturates such as phenobarbital (luminal) cancer chemotherapy epinephrine (epipen) ipratropium (atrovent)medications for anxiety, irritable bowel disease, mental illness, motion sickness, parkinsons disease, seizures, ulcers, or urinary problems monoamine oxidase (mao) inhibitors such as isocarboxazid (marplan), phenelzine (nardil), tranylcypromine (parnate), and selegiline (eldepryl, emsam, zelapar) narcotics and other pain medication sedatives sleeping pillsand tranquilizers. Promethazine is also used to relax and sedate patients before and after surgery, during labor, and at other times. Call your doctor if you experience any unusual problems while you are taking this medication. Promethazine should not be given to babies or children who are younger than 2 years old and should be given with caution to children who are 2 years of age or older.

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